Marco Vignuzzi studied Microbiology and Immunology as an undergraduate at McGill University, and Fundamental Virology as a graduate student at the University of Paris. As a postdoc he studied under Raul Andino, and established his own lab at the Institut Pasteur in Paris in 2008. His lab currently is a 50/50 mix of experimental evolution lab and computational group. The lab focuses attention on medically relevant RNA viruses. The study models include several enteroviruses (EV71, polio, Coxsackievirus, rhinovirus); alphaviruses (chikungunya, O’nyong’nyong, Sindbis, Mayaro); flaviviruses (Zika, dengue, West Nile, Yellow fever, Usutu); and influenza virus. Lab members study the population dynamics and evolution of these viruses in animal models (mostly lab mice and wild mosquitoes, but also Zebrafish and Drosophila). The lab has partnerships with several labs in every tropical region of the world with whom they tackle projects in field settings. The lab combines experimental evolution and computation to generate new antiviral approaches that are of interest to both public health and industry.